The MATH+ protocol developed by world-leading critical care doctors is saving lives and keeping patients off ventilators. In hospitals where it is given soon enough, deaths from COVID-19 are near zero.
MATH+ =
Methylprednisolone
Ascorbate (IV vitamin C)
Thiamine etc. (optional)
Heparin (full-dose)
+ etc. (see protocol details)
Eastern Virginia Medical School MATH+ protocol (16 pg.)
Eastern Virginia Medical School MATH+ protocol summary (2 pg.)
Front Line Covid-19 Critical Care Working Group protocol summary (1 pg.)
“We administered our IV cocktail and within two days you could see a complete difference. He was never intubated. With the MATH+ protocol I have zero percent mortality. Jeff (Boney, the patient in the video) is the reason I went to medical school. You see a man that doesn’t look too good and may end up dead. And he walks out of the hospital and then actually you become his friend. That to me is the best payment I could have. I’ve found a therapeutic intervention that works and I’m going to spread the word.”
Joseph Varon, MD, FACP, FCCP, FCCM, FRSM
Chairman of the Board, United General Hospital
Chief of Staff and Chief of Critical Care Services, United Memorial
Medical Center/United General Hospital
Professor of Acute and Continuing Care, The University of Texas Health
Science Center at Houston
Professor of Medicine and Surgery, UAT, BUAP, UNE, USON, UABC, UPAEP-Mexico
President, Dorrington Medical Associates, PA
Houston, Texas
Dr. Pierre Kory’s May 6 Senate testimony about the MATH+ protocol:
PDF transcript of Dr. Kory’s testimony:
Drs. Varon, Kory and six other leading critical care doctors have formed the Front Line Critical Care COVID-19 Working Group.
Pierre Kory, MD, MPA
Medical Director, Trauma & Life Support Center
Critical Care Service Chief
Associate Professor of Medicine
University of Wisconsin School of Medicine & Public Health
G. Umberto Meduri, MD
Professor of Medicine
Division of Critical Care & Sleep Medicine
University of Tennessee Health Science Center
Memphis, Tennessee
Paul E. Marik, MD, FCCM, FCCP
Endowed Professor of Medicine
Chief, Division of Pulmonary & Critical Care Medicine
Eastern Virginia Medical School
Norfolk, Virginia
Jose Iglesias, DO
Associate Professor, Hackensack Meridian School of Medicine at Seton Hall
Department of Nephrology & Critical Care, Community Medical Center
Department of Nephrology, Jersey Shore University Medical Center
Neptune, New Jersey
Fred Wagshul, MD
Pulmonologist & Medical Director, Lung Center of America
Clinical Instructor, Wright State University School of Medicine
Dayton, Ohio
Keith Berkowitz, MD, MBA
Medical Director, Center for Balanced Health
Voluntary Attending Physician, Lenox Hill Hosp.
New York, New York
Howard Kornfeld, M.D.
Medical Director, Recovery Without Walls
Diplomate, American Board of Emergency Medicine
Mill Valley, California
— At Sentara Norfolk General Hospital, Norfolk, VA, Paul E. Marik et al. showed a 73% reduction in deaths from sepsis ( Chest journal, June 2017):
— At Ann & Robert H. Lurie Children’s Hospital of Chicago, Eric Wald, et al. found a 68% reduction in 30-day mortality and 60% reduction in 90-day mortality ( Critical Care Medicine , January 2020):
— Key features of these protocols were incorporated, plus the use of heparin to address the hyper-coagulability of COVID-19, in the Shanghai Medical Association Expert Consensus protocol used successfully in Chinese hospitals ( Chinese Journal of Infectious Diseases , March 2020):
— The Eastern Virginia Medical School protocol developed by Dr. Marik et al. (first released in March, 2020) incorporates insights from previous studies and hands-on work with COVID-19 in centers around the world. It is updated frequently as clinical experience develops.
— Two studies have raised controversy, claiming to have been unable to demonstrate benefit. Both suffered from serious flaws in study design or execution (failure to consider “significant” a 78% reduction in mortality, survivor bias, extended delays before beginning key parts of treatment, etc.).
Experience in ICUs where the protocols are being given bears out their effectiveness.
