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Vitamin D
Sugar can increase the expression of the enzyme, 24-hydroxylase, that reduces vitamin D AND can reduce the enzyme 1α-hydroxylase that synthesizes vit D
1α-hydroxylase VD3 1A hydroxylase is located in the proximal tubule of the kidney and a variety of other tissues, including skin (keratinocytes), immune cells, and bone (osteoblasts)
The enzyme catalyzes the hydroxylation of Calcifediol to calcitriol (the bioactive form of Vitamin D)
Calcium, is technically part of number one as it goes hand in hand with vit D – a study published in Hormone and Metabolic Research found that sugar consumption elevates calcium excretion by the kidneys
Chromium
Two studies have found that an increase in sugar consumption, which elevates insulin, results in increased urinary excretion of chromium
Study #1 – Metabolism
Thirty-seven subjects, 19 men and 18 women, consumed reference diets for 12 weeks formulated by nutritionists to contain optimal levels of protein, fat, carbohydrate, and other nutrients; the following 6 weeks, subjects consumed high sugar
Consumption of the high sugar diets increased urinary Chromium losses from 10% to 300% for 27 of 37 subjects
Study #2 – American Journal of Clinical Nutrition
Eleven male and nine female adult subjects were given one of the following five carbohydrate-drink combinations (per kg body wt) on five mornings separated by greater than or equal to 2 wk: 1) 1.0 g glucose, 2) 0.9 g uncooked cornstarch, 3) 1.0 g glucose followed 20 min later by 1.75 g fructose, 4) 0.9 g uncooked cornstarch followed 20 min later by 1.75 g fructose, and 5) water followed 20 min later by 1.75 g fructose
Subjects with the highest concentrations of circulating insulin displayed decreased ability to mobilize chromium on the basis of urinary chromium excretion.
Researchers concluded that ““urinary chromium losses are related to the insulinogenic properties of carbohydrates.”
Magnesium
A study from the Journal of Clinical Investigation concluded that “…glucose ingestion reduce the renal tubular reabsorption of magnesium and (or) calcium, but they act through separate mechanisms.”
Vitamin C
A study from American Journal of Nephrology found that:
The charged form of vitamin C, ascorbate, is taken up into cells via sodium-dependent facilitated transport
The uncharged form, dehydroascorbate, enters cells via glucose transporter and is then converted back to ascorbate within these cells
Because dehydroascorbate and glucose compete for glucose transporters, hyperglycemia will exclude vitamin C from the cell and resulted in a decreased antioxidant capacity in some cell type that is dehydroascorbate dependent
Fasting Guides
How to do Intermittent Fasting: Complete Guide:
Complete Women’s Guide to Intermittent Fasting:
Fasting Guidelines: What You CAN and CANNOT Drink:
Intermittent Fasting over Age 40 : The Complete Guide:
Keto Guides
How to do a Keto Diet: The Complete Guide:
Full Beginner Keto Meal Plan: Exactly What to Eat:
