Note: I meant to say increase pH not decrease pH.
HCQ:
Reduces virus fusion with the cell membrane.
Causes basic cellular environment that reduces virus replication
Allows Zinc to enter the cell.
Changes the glycation of the ACE2 receptor making its binding affinity less for the SARS-COV-2
This is why Astragalus is having excellent results in China to prevent and weaken Covid19…
Dr. Gautret
Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
No evidence of rapid antiviral clearance or clinical benefit with the combination of hydroxychloroquine and azithromycin in patients with severe COVID-19 infection
Chinese study
Ongoing studies
NYU
ORCHID
PATCH Trial