This is a continuation of the last episode where Dr. Patrick took questions from newsletter subscribers around the on-going pandemic and tried to add value by talking about some of the recent research, among other things.
Some of the topics that came up as a result of the questions submitted include:
• 00:04:03 – Data surrounding SARS-CoV-2 duration
• 00:06:37 – SARS-CoV-2 and potential immunity
• 00:11:35 – Some of the main factors known to play a role in immune variation
• 00:12:05 – What role genetics may play in immune function
• 00:14:27 – How previous viral exposure regulates immunity
• 00:15:05 – What cross immunity is and how it may be relevant for SARS-CoV-2
• 00:19:46 – Antibody-dependent enhancement and SARS-CoV-2 relevance
• 00:21:50 – How sleep is a key regulator of immune function
• 00:23:44 – Microbiome composition and immune function
• 00:28:31 – The differential effects of exercise intensity and duration on immune regulation
• 00:35:00 – How specific micronutrient inadequacies may promote immune dysregulation
• 00:47:20 – The effect of sex hormones on immune function
• 00:48:55 – How biological age age may play a role in immune regulation
• 00:49:46 – Controversy surrounding hypertension drugs such as ACE inhibitors and COVID-19
• 00:53:15 – ARDS and long-term lung damage
You can find this episode page along with a very detailed summary with references at
This episode mentions a number of genetic polymorphisms that affect viral entry into the host cell, viral replication, host immune response ranging from cytokine production to viral-induced inflammation, SNPs that affect vitamin D levels, and more. If you have used any consumer-based genetic testing services like 23andMe or Ancestry DNA we have a free viral report with these SNPs that you can check out. You can find that at
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