Researchers at the NIH and ModeRNA are using messenger RNA (or mRNA) to teach your body’s immune cells important features of the new coronavirus, specifically the spike proteins that are used by the virus to interact with the ACE-2 receptors on host cells during infection. By administering mRNA to an antigen presenting cell (APC), your body’s immune system may be able to better recognize and block the coronavirus to protect from COVID-19. Two Phase 1 clinical trials are currently underway to demonstrate this new drug’s safety.
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