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5 Supplements Dave Asprey Couldn’t Live Without
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Timestamps ⏱
0:00 – Intro
0:10 – Vitamin “DAKE”
0:35 – Minerals 101
1:55 – Dessicated Grass-Fed Beef Liver
2:47 – 30% Off Your First Order AND a Free Gift Worth up to $60
3:48 – Dessicated Grass-Fed Beef Liver
5:31 – Glutathione
10:14 – Modafinil
17:22 – Where to Find More of Dave’s Content
All right Dave asprey if you could only have a few supplements for the rest of your life what would they be number one vitamin D uh vitamin D A ke you can go to vitamind d.com to get the full ratio of these things but vitamin D3 vitamin A vitamin
K2 and a small amount of vitamin E if you have those things they will tell tell your body where to put minerals the second one would be minerals 101 from that same vitamin day site minerals 101 is basically a blend of the macro minerals that you need everyone today is mineral
Deficient because our plants and our animals are deficient because our soil isn’t being treated well glyphosate’s a part of it industrial farming is a part of it and if you’ve grown plants in the soil for hundred years what makes you think those plants have minerals in them
Where are they going to get the minerals right so they’re deficient on top of that the health foods whole grains nuts seeds beans they all contain phytic acid that sucks minerals out of your bones you need minerals to make testosterone you need minerals to make electricity in your
Cells so the combination of vitamin day and minerals 101 or a blend of macro minerals equals now your body can do what it’s supposed supposed to do otherwise you’re going to exercise you’re going to put in the stimulus to change the body says I wanted to change
But I didn’t have any zinc and I didn’t have potassium and I didn’t have chromium I couldn’t make the things I was supposed to make so how about having some low grade anxiety which is physical stress instead of having some adaptation this is why those are so
Important the third I would do would be desiccated grass-fed beef liver which is one of the first things I gave to my baby B when they stop nursing and it’s something that’s been in my handful of supplements most days but not all up to the equivalent of 1 oce of fresh beef
There is a case against eating a large amount of organ meat every day it raises uric acid very very meaningfully so a diet of you know two pounds of liver a day and six balls and three pancreases it’s going to raise your U acid levels to a point that that’s not really good
For you you take my word for it or you listen to my interview with David pearlmutter has he been on your show no he has you should have him on absolute rock star a doctor and he wrote a book called drop acid that talks about uric acid and metabolism and what that’s
Doing for aging and things like that he has a very strong case on this so organ means good too much organ meat probably not so good I put a link down below for Thrive Market I know this is a relevant pitch for them but at the same time it
Makes sense there’s a 30% off discount link down below Thrive Market is an online membership based grocery store store and it literally is their mission to make healthier food more available for people in areas that cannot get healthier food they really wanted to make sustainability a real thing and be
Able to get real good unprocessed and even healthier processed food options into people’s hands so that link down below is a 30% off discount link for whatever you choose you can fill up your grocery cart using that link 30% off plus a free $60 gift so 30% off whether
You choose some beet chips or whether you choose cete tortilla chips instead of regular corn chips or if you want jerky snacks or this or that and a lot of the times it’s going to be much much cheaper than you would find at many grocery stores so that link is down
Below it’s in the top line of the description underneath this video and again 30% off and a free $60 gift and the reason liver is so important it has some minerals like copper but more importantly it has the B vitamins and it has the correct forms of B vitamins a
Lot of people don’t know this but vitamin B6 the form that’s used in 99% of supplements energy drinks is actually bad for you and this is a really important thing it’s called pyod doxine or pyod doxine HCL it is a synthetic form of B6 about 5% of it converts into the form your
Body can use the other 95% of synthetic latches on to your B6 receptors and clogs them up for a thousand days I don’t take supplements with vitamin B6 I take supplements with p5p the methylated form of vitamin B6 it’s very important so if you’re just taking
100 mgram of pyod oxine which a lot of people are getting that is 10 times more than you ought to be getting and it causes peripheral neuropathy or numbness in your limbs there there are people who have B6 toxicity listening to the show right now and don’t know it and they’re
Drinking an energy drink full of B6 so you got to watch out for that is there a way to like clear that faster than a th days no D you don’t need any B6 unless it’s p5p I’m lucky I have the genetics where I need extra vitamin B6 but I can’t take
Pyrro oxine because if I took the levels that my body needs of that I would have peripheral neuropathy oh wait I do have per peripheral neuropathy that I got many years ago from taking too much B6 so p5p take my word for it don’t take B6
Or just take liver because it has a full range of vitamin B that is in the form your body can use the liver is my vitamin b supplement next next up glutathione and I made glutathione famous in biohacking circles on purpose in the very first articles ever written about biohacking glutathione was
Probably one of the first five supplements I ever recommended glutathione is the primary detoxing molecule in your brain and in your liver and when you get liver damage it’s because you ran out of the ability to make glutathione we are exposed to way more toxins in our environment today than
Mother Nature ever designed so your detox system in your liver that uses glutathione is taxed every single day by taking more glutathione you can protect yourself from getting sick you can make your brain work better you can protect your liver from Tylenol and alcohol if
You use things like that and it can I believe extend your life to have higher levels over time interesting so uh what about the oral use of glutathione is there any issue with the oral use is it orally bioavailable if you take glutathione Orly it will get digested and you won’t
Get the benefits of it at that point you might as well just take Glycine and up to 250 milligrams of vitamin C and you’ll make your own glutathion maybe some in acetal cysteine on top of that so that’s how you do it orally or you
Can take it orally just fine it has to be liposomal there are companies that make dry liposomes I launched the first dry liposome when I was formulating at bulletproof which I’m not there anymore I don’t know if they make that product or not but dry liposomes work the stuff
That you put under your tongue that tastes like sulfur definitely works it just tastes like sulfur and there are two other forms of glutathion that you can take orally that have evidence of working so yes it works orally it also works really really well intravenously uh but I would just say something that
Is designed to be orally available should bypass the digestion step just fine any any downsides to taking it frequently is it something you should only take when you feel run down something you should only take if you’re hung over what’s sort of the uh for the regular person Regular Joe off the
Street is there sort of a protocol they may want to follow with then I would skip one day a week just you don’t want your body to always get adapted to having it you might and this is all theoretical you might downregulate your own production of glutathion which is
Unlikely because it’s just aminos and yeah it’s unlikely but it’s really important that you keep your levels up and things like exercise and eating a good diet and all they can help also can it they can indeed right and some of the the things that we think are healthy
Aren’t healthy and can deplete glutathione like over exercising or a plant-based diet so with uh what about supplementing NAC on top of glutathione is there any evidence to support that that could enhance the uptake of it or enhance the utilization or production of it you know
I’ve seen a few people talk about taking higher doses of NAC sometimes NAC with glycine to get some specific longevity effects this is Manu facturing of glutathion inside the cells versus outside the cells I’ve also seen a lot of problems from people getting too much sulfur from
Doing it that way depending on your genetics I’ve experimented with both and generally I don’t like taking NAC if I’m taking glutathion but for years I took NAC so I think it may be an individual genetic difference is there any reason you don’t like taking NAC I I kind of
Play with it on and off and notice like my recovery tends to be better if I’m doing a lot of aerobic work where I’m putting a lot of stress on my like upper respiratory you know where like run the risk of you know picking up infections or whatever but it’s that’s the only
Time I really feel like I get a little bit more recovery out of it otherwise I actually notice sometimes a negative effect I actually notice like as far as like if I’m in more resistance training block or more sort of training in that like lactate range where I’m like
Between LT1 and lt2 I actually feel like I recover worse but again that’s purely me right it could be you have a problem with sulfur metabolism somewhere CT genes or something or some mtfr thing or it could be that its antioxidant effects are blunting the beneficial effects of
The exercise just like metformin does true you know I’m not a fan of Metformin I I quit using that years ago because of the effect on mitochondria but there’s still people out there you know saying I’m a longevity doctor by the way you can’t extend human life you just have to
Lift all the time take statins and get vaccinated and you can live longer like there’s a big book out there right now I’m like this is not a longevity doctor good marketing though yeah for sure all right so that’s four what’s the big number five here uh the big number
Five is one of my favorite supplements in fact almost everyone is suffering from a deficiency and it’s called modafanil are you familiar with this supplement yep so vitamin mapel and what is this stuff it is a prescription drug that was designed for narcolepsy which is when people fall asleep sleep uncontrollably why would
You take it you might not take it every single day you should have it in your bag when you travel you should have it in the glove box of your car because it is far safer as a stimulant a mental stimulant in fact it’s one of the most
Studied and effective smart drugs on the planet for increasing like your the speed of your typing and your mental focus you should have it because you won’t fall asleep driving because when you land and you’re jet lagged you need to get your family to the hotel or you
Need to get on stage and do something important it will turn your brain back on when you slept in a hotel room full of toxic mold and you wake up feeling hung over and you didn’t even drink and you’re a zombie and you take it and you get your brain back it a
Lifesaver I would not have graduated from whorton without mfo I had mold toxin induced brain damage diagnosed by Dr Daniel aan I could not function and that stuff gave me the mental Edge that I needed to just perform like myself and there’s a very low incidence of side effects about five
Out of a million people similar to Advil um or uh ibuprofen is the the chemical name for that uh there’s an autoimmune skin condition that can be really really dangerous that some people can get and there’s actually information online that you can do a genetic test to
See if you have those genes before you take it if you want to try mapol so it’s something maybe it’s every day maybe it’s not every day some people say it’s addictive the evidence is that it’s not addictive and fact from Deep conversations with a drug and alcohol
Emergency room doctor when I mentioned the addictiveness she actually just laughed and said I don’t see junkies saving that stuff up so is modaal something that’s allowed in professional sports no not in most things but it should be because it improves Athletics as well it’s also improved my meditation
If I look at my brain waves at 40 years as in my meditation company it’s funny model works better so if you wanted to improve your cognition I think everyone’s suffering from a mopal deficiency and I say that kind of laughingly because I wrote a blog post about that a
Dozen years ago and I ended up on ABC Nightline as the only guy who would publicly admit to using it everyone had a literally a bag over their head talking about what it did what’s the uh what’s the mechanism of action there we’re not sure that we understand all of
The mechanisms which is annoying it does it does increase oxygenation but probably not blood flow in the brain we know it raises orexin which is something that happens when you eat protein even turmeric or I should say turmeric extract can raise orexin a little bit but orin’s a is it a
Neurotransmitter we’ll call it a neurochemical just to make sure I don’t Mis categorize it uh that raises alertness something that comes when you eat and for whatever reason um you’re more focused there’s also dopamine effect from it but much less than you see from the other dopamine type of
Drugs it may be a dopamine sensitizer we’re not quite uh but however it works it’s uh it’s a fantastic and interesting pharmaceutical yeah definitely a message there now it’s something that uh you know you see a lot of you know military personnel they use that it’s obviously it’s it’s used in
Lots of different veins what would you say if you had to give it three specific benefits like what would you say the three primary benefits are of mapo M uh it’s longer acting than Aderall and it doesn’t make you want people that’s why the military likes it for Pilots you
Know if you’re flying a $50 million aircraft with a machine gun you should probably be a modol not Aderall it Stacks exceptionally well uh with danger coffee or any other lesser coffee uh so it’s not going to interfere with things like that uh in fact they
They go very very well for writing a lot of my writing is is done with that uh and it increases or I say it decreases your reaction time so it increases your speed so you’re actually faster you can sense reality if you ever watch Limitless the movie I know that the the
Producer or the camera crew tried modhal because if you are aware of your state when you take it the world around you slows down a little bit you find the first week you take it like why is everyone around me so dumb right and it’s and then you have to get over
Yourself and get over your ego there and it’s not that they’re dumb it’s that you’re faster and they’re slower and then you have to learn how to regulate your speed so you’re capable of going fast but you don’t want to be going fast all the time because that would be like
You are an adderal and it doesn’t feel good right so you just suddenly realize it expanded the range of speeds at which Your Body Works and in Limitless when he takes it like everything else slows down for a minute like there’s a shift in perception of time and a shift in
Perception of color because when you take it you end up seeing that colors are slightly more saturated and in Limitless when people take that fictional drug there’s a green tinge that comes over everything so you can sort of see they they deepen the colors and it’s very subtle but that’s how it
Works so you’ve had no negative impact on sleep with it or take it in the morning I’ve done it for jez let’s see yeah it would be 20 23 years I’ve used it so it’s there what’s the halflife like I mean is it something that’s I mean so because you
Don’t see people typically talking about many people taking yeah there’s there it’s not typically affecting circadian rhythms so I mean I’m sure it would if you were taking it at 7 p.m. but well it wouldn’t necessarily so they had to make up a new category of drug for it it’s
Not a stimulant and and you’ll see online it’s a dangerous addictive stimulant dude okay it’s as dangerous as Advil uh it’s not addictive and it’s not a stimulant so maybe some people should do their science research it’s called arousal promoting which means you can take it and go to sleep you just don’t
Want to but if you were to drink a cup of coffee you can’t go to sleep right so so there’s a subtle difference there right so like why would I go to sleep because I have all these ideas coming and like I just need to write this I
Need to get this down i’ got to do this got to get this done so it’s just fantastic for that kind of a thing and I’m sure there’s someone out there who’ find a way to take it for three days and stay awake that would be stupid take one
Today I take one almost every day take one before this interview I took one two a day I took one this morning uh 50 milligrams over thereabouts broke one in half so 50 60 whatever um I took it around 8: a.m. and that’s all I’ve had and probably won’t need another one this
Is my last interview so this is what five number five yeah sloppy fifth is over here well you got four and five so there you go okay uh Dave where can everyone find you and tell us where we can find your your book as well go to
Dave ase.com just redid the website to make 3,000 posts about these topics really easy to find there’s 1,200 hours of my podcast all organized arranged for you we’re building the AI bot out right now go there and go to the human upgrade which is my podcast beautiful Dave
Thanks my man you got it
