FITNESS

What Do Vitamins Actually Do?



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This is the Vitamin Tierlist – vitamins play many important roles in our bodies and the biochemistry that vitamins do is pretty neat!

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*Team*
Writer/Producer – That Chemist (Joey)
Editor/Animator – ReformLabs
Research/Production Assistant – Aldous (Nicholas)
Technical Lead – Polygorg (Georg)
3D Systems Engineer – Robot Chicken
Thumbnail Artist – RinFroggy
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*Acknowledgements*
This video was made possible with help from several members of the TC Discord Community, especially Gocker (protein modelling expertise) & Ballerene (biochemistry expertise). Also @ExplosionsAndFire for the raw yellow chem video!
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*References*
Neurotoxin Tierlist https://youtu.be/6fuCYXU4McQ
Medicosis (corn tortillas) https://youtu.be/lPaU1ToTKz4?t=592
Vitamin B12 part 1 https://www.youtube.com/watch?v=YvEB05xdAy4
Vitamin B12 part 2 https://www.youtube.com/watch?v=AVi_awjWaP4
@MedicosisPerfectionalis has a great series on biochemistry – https://youtube.com/playlist?list=PLYcLrRDaR8_dKo6Nu1Dw1efJGkDpuZGEy

General nutrient information https://www.ncbi.nlm.nih.gov/books/NBK554545/
First vitamins https://doi.org/10.4066/AMJ.2013.1588.
Essential Nutrient an overview https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/essential-nutrient
Early vitamin paper https://doi.org/10.1246/NIKKASHI1880.32.4.
Fat Soluble Vitamins https://www.ncbi.nlm.nih.gov/books/NBK534869/
Water Soluble Vitamins https://www.ncbi.nlm.nih.gov/books/NBK538510/
Vitamin K https://ods.od.nih.gov/factsheets/VitaminK-HealthProfessional/
Vitamin A and Carotenoids https://ods.od.nih.gov/factsheets/VitaminA-HealthProfessional/
Vitamin A and retinoid signaling https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679380/
Consequences of Vitamin A Deficiency https://doi.org/10.3390/IJMS21155570
Vitamin A Toxicity https://www.ncbi.nlm.nih.gov/books/NBK532916/
The Golden Rice Project https://www.goldenrice.org/
Thiamine https://ods.od.nih.gov/factsheets/Thiamin-HealthProfessional/
Dry Beriberi in a Man https://doi.org/10.1186/1752-1947-4-409
Beriberi. https://doi.org/10.1016/0306-9877(95)90115-9
Relevance of N-Heterocyclic Carbenes – https://pubs.acs.org/doi/10.1021/jo300745e
Thiamine Pyrophosphate – an overview https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/thiamine-pyrophosphate
Riboflavin – Health Professional Fact Sheet. https://ods.od.nih.gov/factsheets/Riboflavin-HealthProfessional/
Niacin https://ods.od.nih.gov/factsheets/Niacin-HealthProfessional/
Nixtamalization – an overview https://www.sciencedirect.com/topics/food-science/nixtamalization
Nicotinic Acid Deficiency an overview https://www.sciencedirect.com/topics/medicine-and-dentistry/nicotinic-acid-deficiency
Pantothenic Acid https://ods.od.nih.gov/factsheets/PantothenicAcid-HealthProfessional/
Vitamin B6 https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/
Biotin https://ods.od.nih.gov/factsheets/Biotin-HealthProfessional/
Folate https://ods.od.nih.gov/factsheets/Folate-HealthProfessional/
Vitamin B12 https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
Vitamin C https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/
Vitamin D https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
Vitamin E https://ods.od.nih.gov/factsheets/Vitamine-HealthProfessional/
Vitamin K https://ods.od.nih.gov/factsheets/vitamink-healthprofessional/
Vitamin digestion and absorption – https://www.kegg.jp/pathway/map04977
Biosynthesis of cofactors – https://www.kegg.jp/pathway/map0124

Pathway information:
Vitamin A Retinol https://www.kegg.jp/pathway/map00830
Vitamin B1 Thiamine https://www.kegg.jp/pathway/map00730
Vitamin B2 Riboflavin https://www.kegg.jp/pathway/map00740
Vitamin B3 Niacin https://www.kegg.jp/pathway/map00760+C00153
Vitamin B5 Pantothenic Acid Beta alanine metabolism https://www.kegg.jp/pathway/map00410
CoA synthesis https://www.kegg.jp/pathway/map00770
Vitamin B6 Pyridoxine https://www.kegg.jp/pathway/map00750
Vitamin B7 Biotin https://www.kegg.jp/pathway/map00780
Vitamin B9 Folate/folic acid https://www.kegg.jp/pathway/map00790
Vitamin B12 Cobalamin https://www.kegg.jp/pathway/map00860+M00122
Vitamin C Ascorbic acid https://www.kegg.jp/pathway/map0005
Glutathione https://www.kegg.jp/pathway/map00480
Vitamin D steroid biosynthesis https://www.kegg.jp/pathway/map0010
Vitamin E Tocopherol https://www.kegg.jp/pathway/map00130+M00112
https://www.kegg.jp/pathway/map01110+M00112
Vitamin K Phytonadione https://www.kegg.jp/pathway/map00130+M00932
Relevant human Proteins found in RCSB PDB RCSB.org 10.1093/nar/28.1.235
And predicted proteins found at https://www.uniprot.org/