COVID-19

VITAMIN D IMMUNOLOGY: COVID-19 DISEASE DEFENCE MECHANISMS

Vitamin D deficiency is a global pandemic as is Covid 19. Vitamin D is a powerful immuno-modulator that is found to produce favorable responses of the innate and adaptive immune system. It can also supress the cytokine & bradykinin storm due to the hyperactivity of the renin-angiotensin system. It has action in endothelial stabilisation and prevention of thrombosis.

When checked first time without any supplementation, very low vitamin D levels found in 90% (3 – 20 ng/ml). It is advisable to maintain serum 25-hydroxy vitamin D in the range of 40 – 60 ng/mL to minimize the risk of COVID-19 infection and its severity. Nobody has been found with the minimal desired level 40 ng/ml unless taking Vit D supplements

We lose nothing by improving the global vitamin D status. Correcting a deficiency is our duty, responsibility & obligation as doctors. We can do more good by checking the vitamin D (25 OH D3) blood levels in Covid 19 positive patients (hospitalised and those advised tests for inflammatory markers) and raising the vitamin D levels up immediately.

If not now, then when????