There have been quite a large number of clinical studies on Ivermectin in the treatment/prevention of COVID-19 and the NIH recently eliminated their recommendation against its use in COVID-19! One question has remained though, how might it work in COVID-19? We have covered a multitude of potential mechanisms (linked in the Ivermectin and COVID-19 playlist below!) that have been theorized. This new study, published in Nature, has identified another potential mechanism. Inhibition of the SARS-CoV-2 3-Chymotrypsin-like Protease (3CL-pro), a critical enzyme in the replication cycle of SARS-CoV-2. We illustrate what this enzyme is, how it works, and how it plays a role in the lifecycle of the virus causing COVID-19. We then dive into the paper discussing concentrations of Ivermectin used and future directions. Check out the video for all this and more!
PLAYLIST ON IVERMECTIN AND COVID-19:
OTHER POSSIBLE MECHANISMS OF IVERMECTIN IN COVID-19:
Ivermectin Immunosuppressive Effects in COVID-19:
IVM Binding To Spike Protein And ACE2R:
Four Different Mechanisms of Action Of IVM:
Ivermectin And The STAT3 Pathway: A New Mechanism Of Action:
Ivermectin Inhibits RNA Dependent RNA Polymerase
Ivermectin and new mechanism; halting thrombi through inhibition of CD147:
Link to study:
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There will be a running series of videos using the most up to date information on COVID-19, but this is an evolving field and new videos may come out that contradict that previous information. That is okay and is the nature of a fast paced and evolving clinical scenario. Stick with us as we work to unveil the intricacies of COVID-19, it’s clinical significance, and the societal implications. ***This is strictly educational and not to be mistaken as clinical recommendations, please verify all information with accepted guidelines and practice patterns.***
DISCLAIMER
THIS VIDEO DOES NOT PROVIDE MEDICAL ADVICE. The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read, watched, or listened to on this video, or any other videos, reports, texts tweets or other sources.
