To identify who has an immune response against the #coronavirus. It’s important to detect an antibody called Immunoglobulin G or #IgG. IgG antibodies are proteins produced seven to fourteen days after an infection by the immune system in response to an infection and are specific to that particular pathogen.
People who have been infected by the coronavirus produce distinct IgG antibodies, regardless of whether they had symptoms or not. IgG antibodies bind to the surface of the coronavirus, which has four types of proteins spike, envelope, membrane, and nucleocapsid. The spike protein is the major surface protein that the coronavirus uses to enter human cells.
To identify an immune response against SARS-CoV-2, it’s important to target the right antibodies. Laboratory studies have shown that antibodies against the receptor-binding domain (RBD) of the spike protein are neutralizing in vitro, indicating that they may be a more promising measure of potential immunity when compared to antibodies against other SARS-CoV-2 viral proteins.
This is why Beckman Coulter’s Access SARS-CoV-2 IgG assay detects #antibodies to the RBD of the spike protein.
For more information, visit BeckmanCoulter.com/coronavirus.
