Thiamine tetrahydrofurfuryl disulfide (TTFD) – AKA Thiamax.
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Thiamine tetrahydrofurfuryl disulfide (TTFD) is the synthetic counterpart of allithiamine, occurring naturally in garlic. Thiamax contains thiamine tetrahydrofurfuryl disulfide, a derivative of thiamine (vitamin B1) with high bioavailability. This form has been shown to cross the blood-brain-barrier and can bypass normal routes of thiamine absorption, with a higher rate of uptake both in the gut and at the cellular level.
Unlike other forms of thiamine supplementation, TTFD’s molecular structure allows it to pass through intestinal and cellular membranes without the requirement for a transport system. Once inside the cell, it can be activated and used as a cofactor in important biochemical processes. TTFD also has a demonstrated capacity to penetrate the blood brain barrier and increase thiamine levels in the brain and central nervous system, where it may be used to support optimal cognition and maintain autonomic nervous system function. Due to its superior bioavailability, TTFD can be taken in much lower doses than what is considered the “therapeutic dose” of other forms such as thiamine salts.
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RESEARCH:
Scientific Citations
1Enzymatic Studies on the Metabolism of the Tetrahydrofurfuryl Mercaptan Moiety of Thiamine Tetrahydrofurfuryl Disulfide
2The Effects of Thiamine Tetrahydrofurfuryl Disulfide on Physiological Adaption and Exercise Performance Improvement
3Effect of Thiamine Tetrahydrofurfuryl Disulfide upon the Intestinal Motility
4Benfotiamine and allithiamine should be differentiated
5The Effects of Thiamine Tetrahydrofurfuryl Disulfide on Physiological Adaption and Exercise Performance Improvement
6Thiamine tetrahydrofurfuryl disulfide improves energy metabolism and
physical performance during physical-fatigue loading in rats
7Thiamine tetrahydrofurfuryl disulfide promotes voluntary activity through dopaminergic activation in the medial prefrontal cortex
DISCLAIMER: The information provided in this video is for entertainment purposes only and IS NOT MEDICAL ADVICE. If you have questions about your health contact a medical professional.This content is strictly the opinion of Lucas Aoun and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Lucas Aoun nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.
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