COVID-19

When COVID-19 Attacks, Patient's Cells Turn into Virus Factories

The COVID-19 virus hijacks our cells. Here’s how some treatments might stop it.

It starts at the surface of the cell, when the virus latches on to a protein that normally helps regulate the patient’s blood pressure. The cell unwittingly brings the virus inside, where the attacker unloads its cargo: instructions for making more virus.

Having no equipment of its own, the virus commandeers the cell’s machinery to make copies of its genetic code, manufacture more virus shells and deliver packaged germs to the cell surface, where they go on to infect more cells.

Drugs already on pharmacists’ shelves act on various parts of that machinery. Though they may not be intended as antiviral drugs, in the scramble to treat the rising toll of COVID-19 infections, scientists are hoping that these existing drugs might offer some help.