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The release of cytokine triggers increased vascular permeability; consequently, the leukocytes increasingly migrate to damaged tissues through margination, rolling, adhesion, transmigration, and chemotaxis. Activated leukocytes concurrently launch prostaglandins and inflammatory aspects, and activate the enhance system, producing C3a and C5a parts that eliminate pathogens (Medzhitov, 2008; Straub et al., 2015; Netea et al., 2017).
On the one hand, ROS assists to remove proteins, lipids, and nuclear acids of the damaged cells and trigger immune cells to eliminate foreign microbes through extracellular systems (Zhang et al., 2016). On the other hand, ROS functions as a second messenger to regulate intracellular signaling…
