WhiteBoard style discussion on preliminary reports from Synairgen regarding their randomized, double blinded, placebo controlled trial on SNG001, which is an inhaled interferon beta, for the treatment of COVID-19. They have not yet published the data, so our only information are reports that the company has put out claiming a 79% decrease in mortality/mechanical ventilation and a faster resolution of symptoms as compared to placebo. In this video we will discuss these numbers, what they mean, and what little bit we know so far about the sample population studied. We will also go over the clinical trial itself, including the design and caliber. Lastly, we will discuss the mechanism of action of inhaled interferon beta, why it may work, and what we know so far about its applicability to coronavirus infections, including SARS and MERS.
Link to news article:
Link to clinical trials website:
Link to previous video on IFN beta (mechanism of action, SARS and MERS data):
There will be a running series of videos using the most up to date information on COVID-19, but this is an evolving field and new videos may come out that contradict that previous information. That is okay and is the nature of a fast paced and evolving clinical scenario. Stick with us as we work to unveil the intricacies of COVID-19, it’s clinical significance, and the societal implications. ***This is strictly educational and not to be mistaken as clinical recommendations, please verify all information with accepted guidelines and practice patterns.***
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THIS VIDEO DOES NOT PROVIDE MEDICAL ADVICE. The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read, watched, or listened to on this video, or any other videos, reports, texts tweets or other sources.
